![]() A lack of agglutination or hemolysis indicates a negative test reaction, or compatible match. It is an immediate test that involves combining the patient's serum and donor's red blood cells at room temperature, then centrifuging the sample and observing for agglutination or hemolysis. ![]() Immediate-spin cross-matching (ISCM) is an abbreviated form of cross-matching that is faster, but less sensitive its primary use is to detect a mismatch between ABO blood types. : 263 Cross-matching is also used to determine compatibility between a donor and recipient in organ transplantation. : 600−3 In emergencies, blood may be issued before cross-matching is complete. In some circumstances, an electronic cross-match can be performed by comparing records of the recipient's ABO and Rh blood type against that of the donor sample. Along with blood typing of the donor and recipient and screening for unexpected blood group antibodies, cross-matching is one of a series of steps in pre-transfusion testing. This antibody-antigen reaction can be detected through visible clumping or destruction of the red blood cells, or by reaction with anti-human globulin. If the blood is incompatible, the antibodies in the recipient's plasma will bind to antigens on the donor red blood cells. Normally, this involves adding the recipient's blood plasma to a sample of the donor's red blood cells. Cross-matching or crossmatching is a test performed before a blood transfusion as part of blood compatibility testing.
0 Comments
Leave a Reply. |